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Guduchi, org (1 lb.)


Item Number : 6891 Price: $21.50 Quantity :

USDA Organic

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Certified Organic Guduchi stem powder (Tinospora cordifolia)

An excellent rejuvenative for vata and pitta that supports overall health and well-being.*

   * Bolsters the immune system*
   * Supports proper function of the liver and kidneys*
   * Promotes healthy skin and a clear complexion*
   * Supports digestion and a healthy balance of intestinal flora*
   * Supports comfortable movement of the joints*

Ayurvedic Energetics:

   * Rasa (taste): bitter, astringent, sweet, pungent
   * Virya (action): heating
   * Vipaka (post-digestive effect): sweet
   * Doshas (constitutions): Balancing for all doshas, especially for vata and pitta.

Commentary: The health promoting powers of Guduchi were so respected by the authors of the ancient Ayurvedic texts that they called it 'Amrita' or 'Divine Nectar'. A powerful nutritive tonic, Guduchi is one of the best herbs for balancing vata and pitta. It has the unusual characteristic of being heating while simultaneously removing excess pitta from the body. This heat burns accumulated natural toxins purifying the liver, kidneys, joints and blood. It also helps soothe the skin and promotes a clear, healthy complexion. As a rejuvenative, Guduchi strengthens the tissues, bolsters immunity and promotes vitality while calming the mind and supporting proper function of the nervous system. It is also traditionally used to promote longevity and to support healthy reproduction.*

For a 1/2 lb bag click here For five lbs or more in bulk click here

Herbal tablets that contain Guduchi include: Blood Cleanse, Healthy Vata, Healthy Pitta, Heart Formula, I Sleep Soundly, Joint Support, Kaishore Guggulu , Kidney Formula, Liver Formula, Mahasudarshan, Pitta Digest, Punarnavadi Guggulu, Stress Ease, Sweet Ease, Tranquil Mind, and Women's Support

Other products that contain Guduchi include: Chyavanprash, Joint Balm, Mahanarayan Oil, Pitta Massage Oil, and Soothing Skin Balm

This product is organically grown and processed in accordance with the USDA's National Organic Program (NOP).

For more information on Guduchi visit: Wikipedia's entry for Tinospora cordifolia

Herbs for life: Guduchi monograph

Search index page description Banyan Botanicals Guduchi stem powder is USDA certified organic, sustainably sourced, and fairly traded. Guduchi is also known as Giloy (Hindi), Amrita (Sanskrit), and Heartleaf moonseed (English). The botanical name of Guduchi is Tinospora cordifolia. Guduchi powder is available in 1 lb and 1/2 lb bags and in bulk bags of 5 lbs or more.

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Botanical name: Tinospora cordifolia, Menispermaceae

Other names: Amrita, ‘nectar,’ (S), Gulancha, Gurach (H), Amridavalli, Chintilikoti (T), Tinospora (E), Kuan jin teng (T. sinensis) (C)

GuduchiBotany: Guduchi is a large deciduous perennial climber with large succulent stems and papery bark, sending down long, pendulous fleshy roots as it climbs. The leaves are glabrous and cordate, with 7-9 veins. Guduchi is monoecious with yellowish white flowers with six petals borne on racemes, the male flowers clustered in the axils of small subulate bracts, the female flowers usually solitary, with three carpels. The mature drupes are red in colour, marked with sub-basal style-scar (Kirtikar and Basu 1935, 77-78; Warrier et al 1996, 283).

Part used: Stem.


     Rasa: tikta, kashaya, madhura
     Vipaka: madhura
     Virya: langhana, ushna
     Karma: dipanapachana, grahi, jvaraghna, dahaprashamana, kasahara, kustaghna, hrdaya, chedana, vajikarana, rasayana, tridoshahara (Srikanthamurthy 2001, 228; Dash 1991, 14; Dash and Junius 1983, 139; Kirtikar and Basu 1935, 78; Warrier et al 1996, 283).

Constituents: Researchers have isolated a variety of constituents for Guduchi, including alkaloids, glycosides, steroids, and other compounds. Among the alkaloidal constituents are the isoquinolines berberine and jatrorrhizine, and aporphine-type alkaloids magnoflorine and tembestarine. Glycosides include the bitter tasting gilion, tinocordiside, tinocordifolioside, cordioside, syringin, syringin-apiosylglycoside, palmatosides C and F, cordifolisides A-E, and diterpenoid lactones (clerodane derivatives, tinosporon, tinosporidine, tinosporides, jateorine, columbin). Steroidal constituents consist of ??-sitosterol, ??-sitosterol, tingilosterol, hydroxy ecdysone, ecdysterone, makisterone A and giloinsterol. Other constituents include the sesquiterpenoid tinocordifolin, aliphatic compounds octacosanol, heptacosanol and nonacosan-15-one, a non-glycoside bitter principle called gilenin, and the polysaccharide arabinogalactan (Singh et al 2003; Yoganarasimhan 2000, 547-8; Chintalwar et al 1999; Kapil and Sharma 1997; Gangan et al 1994; Swaminathan et al 1989a; Swaminathan et al 1989b).

Medical research:

Hepatoprotective: The effect of a Tinospora cordifolia extract on carbon tetrachloride intoxication in mature rats was studied. The administration of carbon tetrachloride produced hepatic damage, estimated by the elevation of liver enzymes (i.e. SGOT, SGPT, ALP) and bilirubin in the serum, and immunosuppressive effects. Treatment with T. cordifolia extract (100 mg/kg body weight for 15 days) in the intoxicated rats was found to protect the liver, inferred by a significant reduction in serum levels of SGOT, SGPT, ALP, and bilirubin. T. cordifolia also inhibited the immunosuppressive effect of carbon tetrachloride, producing a significant increase in the functional capacities of rat peritoneal macrophages (Bishayi et al 2002). Tinospora cordifolia was evaluated for its effect on Kupffer cell function, using a carbon clearance test as an assessment parameter. In rats receiving horse-serum for 12 weeks the half-life of carbon was found to be significantly increased, indicating suppressed Kupffer cell function. In rats treated with Tinospora cordifolia the carbon half-life was found to be significantly decreased compared vehicle controls, indicating a significant improvement in Kupffer cell function and a trend towards normalization (Nagarkatti et al 1994). Thirty patients with extrahepatic obstructive jaundice with sepsis were divided into two groups, group one receiving conventional management, including vitamin K, antibiotics and biliary drainage, and group two, which received an extract of Tinospora cordifolia (16 mg/kg/day orally) in addition to biliary drainage. Results showed that hepatic function remained comparable in the two groups after drainage, but that the phagocytic and killing capacities of neutrophils normalized only in patients receiving Tinospora cordifolia. Post-drainage bactobilia was observed in 8 patients in group one and 7 in group two, whereas clinical evidence of septicemia was observed in 50% of patients in group one, compared with none in group two. Post-operative survival in groups one and two was 40% and 92.4% respectively (Rege et al 1993). A clinical study determined that patients with obstructive jaundice have a significant depression in the phagocytic and microbicidal activity of polymorphonuclear cells. To study this issue further, and the benefit of Guduchi in obstructive jaundice, researchers developed an animal model of cholestasis, in which the activity of PMN and peritoneal macrophages was similarly observed. The experimental animals were also succeptible to E. coli infection. Upon treating the rats with a water extract of T. cordifolia 100 mg/kg for 7 days cellular immune functions were improved and mortality rates following E. coli infection were significantly reduced to 16.67% (Rege et al 1989).

Diabetes: The anti-hyperglycemic effect of aqueous and alcoholic extracts of Tinospora cordifolia (TC) was evaluated in diabetic animals using different doses of diabetogenic agents. In mild diabetes there was maximum reduction in glucose levels of 70.37% in animals receiving 400 mg/kg per day of an aqueous extract of TC. The percent reduction in glucose in moderate diabetes was 48.81%, and 0% for severe diabetes (Grover et al 2000). The oral administration of 2.5 g and 5.0 g/kg body weight of the aqueous extract of Tinospora cordifolia for 6 weeks resulted in a significant reduction in thiobarbituric acid reactive substances (TBARS) and an increase in reduced glutathione (GSH), catalase (CAT) and superoxide dismutase (SOD) in alloxan diabetic rats. The greatest effects were most prominent when the extract was given in higher doses, and was more effective than glibenclamide (Stanely et al 2001). The oral administration of an aqueous extract of T. cordifolia root in alloxan diabetic rats promoted a significant reduction in blood glucose and brain lipids, increasing body weight, total haemoglobin and hepatic hexokinase, and reducing hepatic glucose-6-phosphatase and serum acid phosphatase, alkaline phosphatase, and lactate dehydrogenase (Stanely et al 2000). The oral administration of an aqueous extract of T. cordifolia root, 2.5 and 5.0 g/kg given for 6 weeks resulted in a decrease in the levels of plasma thiobarbituric acid reactive substances, ceruloplasmin and ?-tocopherol in alloxan diabetic rats. The root extract also promoted an increase in the levels of glutathione and ascorbic acid in alloxan diabetes. Overall, the effect of the extract was more effective than glibenclamide, restoring insulin parameters to near normal levels (Prince and Menon 1999). The administration of an extract of T. cordifolia roots, 2.5 and 5.0 g/kg body weight for 6 weeks resulted in a significant reduction in serum and tissue cholesterol, phospholipids and free fatty acids in alloxan diabetic rats. The root extract dosed at 5.0 g/kg body weight demonstrated the highest hypolipidaemic effect (Stanely et al 1999). The aqueous, alcoholic, and chloroform extracts of the leaves of Tinospora cordifolia were administered in doses of 50, 100, 150 and 200 mg/kg body weight in normal and alloxan-diabetic rabbits. The blood glucose and total lipid levels were estimated before and 2, 4, 6, and 8 hours after administration of the extract. The extract exerted a significant hypoglycaemic effect in normal as well as in alloxan-treated rabbits, suggesting an insulin-like action (Wadood et al 1992).

Immune: The aqueous and ethanol extract of the stems of Tinospora cordifolia was found to inhibit immunosuppression and anemia induced by cyclophosphamide in experimental animals (Manjrekar et al 2000). Syringin and cordiol isolated from Tinospora cordifolia inhibited the in vitro immunohaemolysis of antibody-coated sheep erythrocytes by guinea pig serum, dose-dependently enhancing humoral and cell-mediated immunity. Macrophage activation was reported for cordioside, cordiofolioside A, and cordiol, constituents isolated from Tinospora cordifolia (Kapil and Sharma 1997). Researchers demonstrated that after 10 days of treatment with Tinospora cordifolia (100 mg/ kg/d), the extract induced a significant increase in the number of colony forming unit-granulocyte/macrophage units in the serum of mice, suggesting that the extract activates macrophages, leading to leucocytosis and improved neutrophil function (Thatte et al 1994). Pretreatment with Tinospora cordifolia significantly reduced mortality in E. coli induced peritonitis in mice, improving bacterial clearance as well as the phagocytic and intracellular bactericidal capacities of neutrophils. Tinospora cordifolia however did not possess an in vitro bactericidal activity, the results demonstrating an immmunostimulant effect for Tinospora (Thatte et al 1992).

Antitumor: The exposure of HeLa cells to 0, 5, 10, 25, 50 and 100 microg/ml of methanol, aqueous and methylene chloride extracts of Guduchi resulted in a dose-dependent but significant increase in cell killing when compared to non-drug-treated controls. The effect of the Guduchi extracts was comparable or better than doxorubicin treatment (Jagetia et al 1998).

Antioxidant: An extract of Tinospora cordifolia was found to inhibit lipid peroxidation and superoxide and hydroxyl radicals in vitro. The extract was also found to reduce the toxic side effects of cyclophosphamide administration in mice, and partially reduce elevated lipid peroxides in serum and liver as well as alkaline phosphatase and glutamine pyruvate transaminase (Mathew and Kuttan 1997).

Toxicity: No data found.

Indications: Dyspepsia, vomiting, hypochondriac pain, flatulence, intestinal parasites, intermittent and chronic fever, burning sensations, cough, asthma, cardiac debility, hepatitis, jaundice, anemia, skin diseases, thirst, debility and weakness, gout, arthritis, disorders of the genitourinary tract, diabetes

Contraindications: Pregnancy.

Medicinal uses: According to tradition, Guduchi is said to have origination from the epic battle of the Ramayana in which the God-king Rama lays siege to the island of Lanka, home of the evil King Ravana. When Ravana is finally defeated King Indra is so pleased with the result that he sprinkles amrita (nectar) on the bodies of the slain monkeys to bring them back to life. In all the places where the nectar dribbled down from the bodies of the monkeys, the Guduchi plant is said to have grown. For this reason Guduchi is also called Amrita, but also because Guduchi is one of the best agents in the materia medica of India to treat ama conditions without aggravating or upsetting the doshas. To this extent Guduchi is tridoshahara, the kashaya and tikta rasa pacifying Pitta and Kapha, and the madhura vipaka and ushna virya reducing Vata. It is particularly suited in chronic debilated conditions with autotoxicity, clearing the body of accumulated wastes (ama), stimulating digestion (agni), and restoring the energy systems of the body (ojas). It is widely used by Ayurvedic physicians for a variety of conditions, and finds its way into many different formulations, especially in the treatment of diabetes, in which it is often combined with Shilajitu. Guduchi is often used along with circulatory stimulants such as Shunthi (Zingiber officinalis) in the treatment of amavata (rheumatoid arthritis), to reduce the symptoms of inflammation and pain. Although classified in many nighantus as warming in energy, the balance between its bitter and sweet tastes also makes Guduchi specific to disorders and deficiencies of the liver, blood, and skin, and to reduce the vitiations of Pitta. Thus Guduchi is often used to treat liver disorders, including hepatitis and jaundice, as well as anemia. The Bhavaprakasha mentions a series of formulations called Guduchi ghrita, the simplest forms prepared from a decoction of Guduchi dried herb or fresh juice, with ghee and water, in the treatment of gout, leprosy, jaundice, anemia, splenomegaly, cough and fever (Srikanthamurthy 2000, 402). According to the Chakradatta a similar preparation made with sesame oil is used for a similar range of conditions, including itching and ringworm (Sharma 2002, 236). In the treatment of all types of jvara or fever, with loss of appetite, nausea, thirst and vomiting, the Bhavaprakasha recommends a decoction called Guduchi kvatha, comprised of equal parts Guduchi, Danyaka (Coriander sativum), Nimba, Padmaka (Prunus puddum) and Raktachandana (Pterocarpus santalinus) (Srinkanthamurthy 2000, 17). In the treatment of vomiting, the Chakradatta recommends a cold infusion (hima) with honey (Sharma 2002, 169). As a rejuvenative the Chakradatta recommends Guduchyadi rasayana, comprised of equal parts powders of Guduchi, Vidanga, Shankapushpi, Vacha, Haritaki, Kushta, Shatavari and Apamarga (Achyranthus aspera), taken with ghee as an anupana. The Chakradatta states that this formula “…makes one capable of memorizing a thousand stanzas in only three days” (Sharma 2002, 626).


• Churna: 3-5 g b.i.d.-t.i.d. • Kvatha: 30-90 mL b.i.d.-t.i.d. • Tincture: fresh stem, 1:2, 95%; 2-5 mL b.i.d.-t.i.d.

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tinospora_cordifolia.txt · Last modified: 2018/02/26 18:13 (external edit)